| Issue Date |
Song |
Artist |
| January 5 |
"Low" |
Flo Rida featuring T-Pain |
| January 12 |
"Low" |
Flo Rida featuring T-Pain |
| January 19 |
"Low" |
Flo Rida featuring T-Pain |
| January 26 |
"Low" |
Flo Rida featuring T-Pain |
| February 2 |
"Low" |
Flo Rida featuring T-Pain |
| February 9 |
"Low" |
Flo Rida featuring T-Pain |
| February 16 |
"Low" |
Flo Rida featuring T-Pain |
| February 23 |
"With You" |
Chris Brown |
| March 1 |
"With You" |
Chris Brown |
| March 8 |
"With You" |
Chris Brown |
| March 15 |
"With You" |
Chris Brown |
| March 22 |
"With You" |
Chris Brown |
| March 29 |
"With You" |
Chris Brown |
| April 5 |
"Love In This Club" |
Usher featuring Young Jeezy |
| April 12 |
"Sexy Can I" |
Ray J & Young Berg |
| April 19 |
"Sexy Can I" |
Ray J & Young Berg |
| April 26 |
"Sexy Can I" |
Ray J & Young Berg |
| May 3 |
"Lollipop" |
Lil Wayne featuring Static Major |
| May 10 |
"Lollipop" |
Lil Wayne featuring Static Major |
| May 17 |
"Lollipop" |
Lil Wayne featuring Static Major |
| May 24 |
"Lollipop" |
Lil Wayne featuring Static Major |
| May 31 |
"Lollipop" |
Lil Wayne featuring Static Major |
| June 7 |
"Lollipop" |
Lil Wayne featuring Static Major |
| June 14 |
"Lollipop" |
Lil Wayne featuring Static Major |
| June 21 |
"Lollipop" |
Lil Wayne featuring Static Major |
| June 28 |
"Lollipop" |
Lil Wayne featuring Static Major |
| July 5 |
"Lollipop" |
Lil Wayne featuring Static Major |
| July 12 |
"Lollipop" |
Lil Wayne featuring Static Major |
| July 19 |
"Lollipop" |
Lil Wayne featuring Static Major |
| July 26 |
"Get Like Me" |
David Banner featuring Chris Brown & Yung Joc |
| August 2 |
"Get Like Me" |
David Banner featuring Chris Brown & Yung Joc |
| August 9 |
"I Luv Your Girl" |
The-Dream |
| August 16 |
"I Luv Your Girl" |
The-Dream |
| August 23 |
"A Milli" |
Lil' Wayne |
| August 30 |
"Dangerous" |
Kardinal Offishall featuring Akon |
| September 6 |
"Dangerous" |
Kardinal Offishall featuring Akon |
| September 13 |
"Got Money" |
Lil Wayne featuring T-Pain |
| September 20 |
"Got Money" |
Lil Wayne featuring T-Pain |
| September 27 |
"Whatever You Like" |
T.I. |
| October 4 |
"Whatever You Like" |
T.I. |
| October 11 |
"Whatever You Like" |
T.I. |
| October 18 |
"Whatever You Like" |
T.I. |
| October 25 |
"Whatever You Like" |
T.I. |
| November 1 |
"Whatever You Like" |
T.I. |
| November 8 |
"Whatever You Like" |
T.I. |
| November 15 |
"Whatever You Like" |
T.I. |
| November 22 |
"Live Your Life" |
T.I. featuring Rihanna |
| November 29 |
"Live Your Life" |
T.I. featuring Rihanna |
| December 6 |
"Live Your Life" |
T.I. featuring Rihanna |
| December 13 |
"Live Your Life" |
T.I. featuring Rihanna |
| December 20 |
"Live Your Life" |
T.I. featuring Rihanna |
| December 27 |
"Live Your Life" |
T.I. featuring Rihanna |